Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

Completed · Not applicable

Conditions studied: Kidney Disease

In brief

Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.

Key facts

Study ID

NCT00018785

Run by

US Department of Veterans Affairs

Starts

1998-10-01

Expected to finish

2003-09-01

Last updated by the study team

2009-01-21

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

Where it is running

• VAMC Miami — Miami, Florida, United States

Full record on ClinicalTrials.gov

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