Genetics, Metabolism and Weight Loss in Older, Obese Veterans

Completed · Not applicable

Conditions studied: Obesity

In brief

This study is designed to determine whether sequence variation in the lipoprotein lipase (LPQ) gene affects the amount of weight loss and metabolic responses during a hypocaloric diet treatment for overweight and obese (BMI=25-35 kg/m2), older (50-65 yrs), sedentary veterans.

Key facts

Study ID

NCT00018330

Run by

US Department of Veterans Affairs

Starts

1999-04-01

Expected to finish

2004-03-01

Last updated by the study team

2009-01-21

Who can join

Age: 50 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Diabetes,
• Hypertriglyceridemia (>400 mg/dl),
• History of cancer or myocardial infarction,
• Clinical depression,
• Renal, liver or hematologic disease, and
• Medications that affect glucose or lipid metabolism (thiazides, estrogen replacement, beta-blockers).

Where it is running

• VA Maryland Health Care System — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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