The Effect of Exercise Training on Mental Stress-Induced Silent Ischemia

Completed · Not applicable

Conditions studied: Myocardial Ischemia

In brief

Coronary artery disease (CAD) remains the leading cause of death in the elderly. Silent myocardial ischemia (SI) is a manifestation of CAD in which there is a transient alteration in myocardial perfusion, function, and/or electrical activity not accompanied by chest pain. Mental and emotional stress, in particular hostility and anger are potent inducers of SI, Individuals with SI are at a 3-5 fold higher risk for the development of angina, myocardial infarction and death than subjects without SI.

Key facts

Study ID

NCT00018252

Run by

US Department of Veterans Affairs

Starts

1997-04-01

Expected to finish

2000-03-01

Last updated by the study team

2009-01-21

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

• VA Maryland Health Care System — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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