Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis

Completed · Phase 1

Conditions studied: Multiple Sclerosis

In brief

OBJECTIVES: I. Determine the efficacy, in terms of disease progression, of high-dose cyclophosphamide and total body irradiation with T lymphocyte-depleted autologous peripheral blood stem cell or bone marrow rescue in patients with multiple sclerosis.

Key facts

Study ID

NCT00017628

Run by

Northwestern Memorial Hospital

People needed

20

Starts

2001-04-01

Last updated by the study team

2005-06-24

Who can join

Age: any, up to 59. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Northwestern Memorial Hospital — Chicago, Illinois, United States
• Rush-Presbyterian-St. Luke's Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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