Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic Syndrome

Completed · Phase 2

Conditions studied: Myelodysplastic Syndromes

In brief

RATIONALE: Immunosuppressive therapy may improve bone marrow abnormalities and may be effective treatment for myelodysplastic syndrome. It is not yet known whether immunosuppressive therapy is more effective than supportive care in treating myelodysplastic syndrome. PURPOSE: Randomized phase II trial to compare the effectiveness of antithymocyte globulin with that of supportive care in treating patients who have myelodysplastic syndrome.

Key facts

Study ID

NCT00017550

Run by

Genzyme, a Sanofi Company

Starts

2000-09-01

Expected to finish

2003-11-01

Last updated by the study team

2021-01-27

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Washington Cancer Institute — Washington D.C., District of Columbia, United States
• University of Florida Health Science Center — Gainesville, Florida, United States
• Sylvester Cancer Center, University of Miami — Miami, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Veterans Affairs Medical Center - Tampa (Haley) — Tampa, Florida, United States
• Winship Cancer Institute of Emory University — Atlanta, Georgia, United States
• Rush Cancer Institute — Chicago, Illinois, United States
• Indiana Blood and Marrow Transplant — Beech Grove, Indiana, United States
• Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
• University of Kansas Medical Center — Kansas City, Kansas, United States
• Tulane University School of Medicine — New Orleans, Louisiana, United States
• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
• University of Missouri Kansas City School of Medicine — Kansas City, Missouri, United States
• Saint Louis University Cancer Center — St Louis, Missouri, United States
• Siteman Cancer Center — St Louis, Missouri, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• Hackensack University Medical Center — Hackensack, New Jersey, United States
• New York Presbyterian Hospital - Cornell Campus — New York, New York, United States
• Mount Sinai Medical Center, NY — New York, New York, United States
• James P. Wilmot Cancer Center — Rochester, New York, United States
• New York Medical College — Valhalla, New York, United States
• Comprehensive Cancer Center at Wake Forest University — Winston-Salem, North Carolina, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
• Texas Oncology P.A. — Dallas, Texas, United States
• Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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