Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer

Completed · Phase 3

Conditions studied: Head and Neck Cancer, Oral Complications, Radiation Toxicity

In brief

RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.

Key facts

Study ID

NCT00017511

Run by

Daiichi Sankyo

Starts

2001-06-01

Expected to finish

2003-03-01

Last updated by the study team

2012-05-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Mobile Infirmary Medical Center — Mobile, Alabama, United States
• Cranial Pain Research — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Alta Bates Comprehensive Cancer Center — Berkeley, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• Radiation Oncology Center - Sacramento — Sacramento, California, United States
• Rebecca and John Moores UCSD Cancer Center — San Diego, California, United States
• Stanford University Medical Center — Stanford, California, United States
• Colorado Otolaryngology Associates — Colorado Springs, Colorado, United States
• University of Connecticut Health Center — Farmington, Connecticut, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• Innovative Medical Research of South Florida, Inc. — Miami, Florida, United States
• Medical College of Georgia Hospital and Clinics — Augusta, Georgia, United States
• Kootenai Medical Center — Coeur d'Alene, Idaho, United States
• University of Illinois at Chicago — Chicago, Illinois, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• Evanston Northwestern Health Care — Evanston, Illinois, United States
• University of Kansas Medical Center — Kansas City, Kansas, United States
• Central Baptist Hospital — Lexington, Kentucky, United States
• James Graham Brown Cancer Center — Louisville, Kentucky, United States
• Study site — Louisville, Kentucky, United States
• Tulane Cancer Center — New Orleans, Louisiana, United States
• Harbor Hospital Center — Baltimore, Maryland, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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