Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer in Patients at Increased Risk

Stopped early · Not applicable

Conditions studied: Ovarian Cancer

In brief

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. It is not yet known whether fenretinide given before surgery is more effective in preventing ovarian cancer than surgery alone. PURPOSE: Randomized clinical trial to compare the effectiveness of fenretinide followed by surgery with that of surgery alone in preventing ovarian cancer in patients who are at increased risk.

Key facts

Study ID

NCT00017134

Run by

Gynecologic Oncology Group

People needed

71

Starts

2002-09-01

Last updated by the study team

2013-06-10

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

• Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
• Colorado Gynecologic Oncology Group P.C. — Aurora, Colorado, United States
• Helen and Harry Gray Cancer Center at Hartford Hospital — Hartford, Connecticut, United States
• George Bray Cancer Center at New Britain General Hospital — New Britain, Connecticut, United States
• Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital — Fort Lauderdale, Florida, United States
• Evanston Northwestern Healthcare - Evanston Hospital — Evanston, Illinois, United States
• St. Vincent Indianapolis Hospital — Indianapolis, Indiana, United States
• Memorial Hospital of South Bend — South Bend, Indiana, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
• Markey Cancer Center at University of Kentucky Chandler Medical Center — Lexington, Kentucky, United States
• William Beaumont Hospital - Royal Oak Campus — Royal Oak, Michigan, United States
• University of Minnesota Medical Center & Children's Hospital - Fairview — Minneapolis, Minnesota, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• CCOP - Cancer Research for the Ozarks — Springfield, Missouri, United States
• St. John's Regional Health Center — Springfield, Missouri, United States
• Hulston Cancer Center at Cox Medical Center South — Springfield, Missouri, United States
• Siteman Cancer Center at Barnes-Jewish Hospital — St Louis, Missouri, United States
• CCOP - Northern New Jersey — Hackensack, New Jersey, United States
• Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
• Roswell Park Cancer Institute — Buffalo, New York, United States
• Mount Sinai Medical Center — New York, New York, United States
• Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
• Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
• McDowell Cancer Center at Akron General Medical Center — Akron, Ohio, United States

Full record on ClinicalTrials.gov

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