Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer
Completed · Phase 2
Conditions studied: Prostate Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Androgens can stimulate the growth of prostate cancer cells. Drugs such as goserelin or leuprolide may stop the adrenal glands from producing androgens. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy, hormone therapy, and radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying giving chemotherapy together with hormone therapy and radiation therapy in treating patients with locally advanced prostate cancer.
Key facts
- Study ID
- NCT00016913
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 34
- Starts
- 2001-05-01
- Expected to finish
- 2008-05-01
- Last updated by the study team
- 2016-07-06
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Lombardi Comprehensive Cancer Center at Georgetown University Medical Center — Washington D.C., District of Columbia, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
- Veterans Affairs Medical Center - Baltimore — Baltimore, Maryland, United States
- UMASS Memorial Cancer Center - University Campus — Worcester, Massachusetts, United States
- Saint Luke's Hospital — Chesterfield, Missouri, United States
- University Medical Center of Southern Nevada — Las Vegas, Nevada, United States
- CCOP - Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- Oswego Hospital — Oswego, New York, United States
- CCOP - Hematology-Oncology Associates of Central New York — Syracuse, New York, United States
- SUNY Upstate Medical University Hospital — Syracuse, New York, United States
- Veterans Affairs Medical Center - Syracuse — Syracuse, New York, United States
- Community General Hospital of Greater Syracuse — Syracuse, New York, United States
- Wayne Memorial Hospital, Incorporated — Goldsboro, North Carolina, United States
- Wayne Radiation Oncology — Goldsboro, North Carolina, United States
- Lenoir Memorial Cancer Center — Kinston, North Carolina, United States
- Wilson Medical Center — Wilson, North Carolina, United States
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University — Columbus, Ohio, United States
- Roper St. Francis Cancer Center at Roper Hospital — Charleston, South Carolina, United States
- Bon Secours St. Francis Health System — Greenville, South Carolina, United States
- CCOP - Greenville — Greenville, South Carolina, United States
- Danville Regional Medical Center — Danville, Virginia, United States
Full record on ClinicalTrials.gov
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