Treating Periodontal Infection: Effects on Glycemic
Completed · Phase 2 · Has a placebo group
Conditions studied: Periodontal Disease, Diabetes Mellitus, Type 2
In brief
The purpose of this project is to obtain important preliminary data necessary to support design of a full scale, multicenter randomized clinical trial (RCT) to evaluate the effect of treating periodontal infection on glycemic control in type 2 diabetes mellitus.
Key facts
- Study ID
- NCT00016835
- Run by
- University of Michigan
- People needed
- 46
- Starts
- 2001-10-17
- Expected to finish
- 2004-09-03
- Last updated by the study team
- 2017-07-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects must be 18 years of age or older,
- have at least six natural teeth,
- have established periodontal disease (established at the screening examination),
- have a history of type 2 diabetes of at least six months with HbAlc > 7.1%.
You may not qualify if…
- Subjects will be excluded from the study if they are presently under the care of a periodontist;
- have had antibiotic treatment within the previous three months;
- have conditions that require antibiotic prophylaxis for dental treatment;
- have allergies to iodine, doxycycline, metronidazole, or chlorhexidine;
- have blood dyscrasias;
- are pregnant or breast feeding;
- have severe cognitive or communication impairment;
- have a cardiac pacemaker;
- are under cancer chemotherapy;
- are medically unstable or have a life expectancy of less than two years;
- are currently taking disulfiram, phenobarbital, lithium, terfenadine, astemizole, or warfarin;
- or are out of town or otherwise unavailable for more than three consecutive months of the year.
Where it is running
- Department of Cariology, Restorative Sciences and Endodontics — Ann Arbor, Michigan, United States
Full record on ClinicalTrials.gov
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