Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
Completed · Phase 3
Conditions studied: Leukemia
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is most effective for treating infants with acute lymphoblastic leukemia. PURPOSE: Randomized phase III trial to compare the effectiveness of different combination chemotherapy regimens in treating infants who have newly diagnosed acute lymphoblastic leukemia.
Key facts
- Study ID
- NCT00015873
- Run by
- Dutch Childhood Oncology Group
- People needed
- 350
- Starts
- 1999-05-01
- Expected to finish
- 2009-12-01
- Last updated by the study team
- 2014-02-17
Who can join
Age: any, up to 1. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States
- St. Anna Children's Hospital — Vienna, Austria
- Hopital Universitaire Des Enfants Reine Fabiola — Brussels, Belgium
- University Hospital Motol — Prague, Czechia
- Hopital Saint-Louis — Paris, France
- University Medical Center Hamburg - Eppendorf — Hamburg, Germany
- Medizinische Hochschule Hannover — Hanover, Germany
- Our Lady's Hospital for Sick Children Crumlin — Dublin, Ireland
- Nuovo Ospedale San Gerardo at University of Milano-Bicocca — Monza, Italy
- Ospedale San Gerardo — Monza, Italy
- Erasmus MC - Sophia Children's Hospital — Rotterdam, Netherlands
- Ostra Sjukhuset — Gothenburg, Sweden
- Birmingham Children's Hospital — Birmingham, England, United Kingdom
- Institute of Child Health at University of Bristol — Bristol, England, United Kingdom
- Addenbrooke's Hospital at Cambridge University Hospitals NHS Foundation Trust — Cambridge, England, United Kingdom
- Leeds Cancer Centre at St. James's University Hospital — Leeds, England, United Kingdom
- Leicester Royal Infirmary — Leicester, England, United Kingdom
- Royal Liverpool Children's Hospital, Alder Hey — Liverpool, England, United Kingdom
- Royal London Hospital — London, England, United Kingdom
- Great Ormond Street Hospital for Children NHS Trust — London, England, United Kingdom
- Central Manchester and Manchester Children's University Hospitals NHS Trust — Manchester, England, United Kingdom
- Sir James Spence Institute of Child Health — Newcastle upon Tyne, England, United Kingdom
- Queen's Medical Centre — Nottingham, England, United Kingdom
- Oxford Radcliffe Hospital — Oxford, England, United Kingdom
Full record on ClinicalTrials.gov
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