Naltrexone in Treatment of Cocaine Dependence - 5

Completed · Phase 2

Conditions studied: Cocaine-Related Disorders

In brief

The purpose of this study is to determine the efficacy of naltrexone in the treatment of cocaine dependence as measured by: 1) decreased urine benzoylecgonine (BE) levels, 2) decreased cocaine use by self-report, 3) decreased cocaine craving, and 4) retention in treatment.

Key facts

Study ID

NCT00015080

Run by

National Institute on Drug Abuse (NIDA)

People needed

0

Starts

1995-05-01

Expected to finish

1996-07-01

Last updated by the study team

2017-01-16

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meet DSM-III-R criteria for cocaine dependency,
• 18 to 65 years of age,
• capable of understanding the study,
• voluntarily signed consent,
• male or non-pregnant female using approved form of birth control.

You may not qualify if…

• abnormal liver function tests (SGOT, SGPT, or GGT greater than twice the normal values),
• opioid use within the last 7 days,
• use of neuroleptics,
• having a severe acute medical problem,
• unable to complete psychiatric rating scales, or
• judged by the investigator to be unlikely to comply with the study protocol

Where it is running

• Cincinnati MDRU — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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