Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma

Completed · Phase 2

Conditions studied: Multiple Myeloma and Plasma Cell Neoplasm

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy. Sometimes the transplanted cells are rejected by the body's tissues. Peripheral stem cell transplantation with the person's own stem cells followed by donor peripheral stem cell transplantation may prevent this from happening. PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy with autologous peripheral stem cell transplantation and donor peripheral stem cell transplantation in treating patients who have multiple myeloma.

Key facts

Study ID

NCT00014508

Run by

Eastern Cooperative Oncology Group

Starts

2001-11-19

Expected to finish

2011-05-27

Last updated by the study team

2023-06-22

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Baptist Cancer Institute - Jacksonville — Jacksonville, Florida, United States
• Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
• Cancer Center at Tufts - New England Medical Center — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• CCOP - Northern New Jersey — Hackensack, New Jersey, United States
• Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School — New Brunswick, New Jersey, United States
• MBCCOP-Our Lady of Mercy Cancer Center — The Bronx, New York, United States
• Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University — Cleveland, Ohio, United States
• MetroHealth's Cancer Care Center at MetroHealth Medical Center — Cleveland, Ohio, United States
• Penn State Cancer Institute at Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States
• Abramson Cancer Center at the University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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