CATIE- Schizophrenia Trial
Completed · Phase 4
Conditions studied: Schizophrenia
In brief
The CATIE Schizophrenia Trial is part of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project. The schizophrenia trial is being conducted to determine the long-term effects and usefulness of antipsychotic medications in persons with schizophrenia. It is designed for people with schizophrenia who may benefit from a medication change. The study involves the newer atypical antipsychotics (olanzapine, quetiapine, risperidone, clozapine, and ziprasidone)and the typical antipsychotics (perphenazine and fluphenazine decanoate). All participants will receive an initial comprehensive medical and psychiatric evaluation and will be closely followed throughout the study. For most participants the study will last up to 18 months. Everyone in the study will be offered an educational program about schizophrenia and family members will be encouraged to participate.
Key facts
- Study ID
- NCT00014001
- Run by
- National Institute of Mental Health (NIMH)
- People needed
- 1600
- Starts
- 2000-12-01
- Expected to finish
- 2004-12-01
- Last updated by the study team
- 2015-06-17
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- LA County-University of Southern California Medical Center — Los Angeles, California, United States
- University of California, Irvine — Orange, California, United States
- University of California,San Diego/VA Medical System — San Diego, California, United States
- Stanford University School of Medicine — Stanford, California, United States
- Harbor UCLA Research & Education Institute — Torrance, California, United States
- New Britain General Hospital — New Britain, Connecticut, United States
- Yale University/Connecticut Mental Health Center — New Haven, Connecticut, United States
- Mental Health Advocates Inc. — Boca Raton, Florida, United States
- VA Medical Center — Miami, Florida, United States
- University of Miami School of Medicine — Miami, Florida, United States
- Emory University School of Medicine — Atlanta, Georgia, United States
- The Queen's Medical Center — Honolulu, Hawaii, United States
- Northwestern Medical School Department of Psychiatry — Chicago, Illinois, United States
- Southern Illinois University School of Medicine — Springfield, Illinois, United States
- University of Iowa Hospital — Iowa City, Iowa, United States
- Psychiatric Research Institute, Outpatient Clinic — Wichita, Kansas, United States
- Louisiana State University Health Services Center — Shreveport, Louisiana, United States
- Clinical Insights, Inc. — Glen Burnie, Maryland, United States
- Massachusetts General Hospital-Freedom Trial Clinic Schizophrenia Program — Boston, Massachusetts, United States
- St. Elizabeth's Medical Center — Boston, Massachusetts, United States
- Corrigan Mental Health Center — Fall River, Massachusetts, United States
- University Of Massachusetts Memorial Health Care — Worcester, Massachusetts, United States
- University of Minnesota School of Medicine — Minneapolis, Minnesota, United States
- University of Mississippi VA Medical Center — Jackson, Mississippi, United States
- Synergy Clinical Research — Chula Vista, California, United States
Full record on ClinicalTrials.gov
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