Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Completed
Conditions studied: Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
In brief
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility. Lead's effects are observed in male partners of infertile couples attending an IVF clinical, in men acting as semen donors in an artificial insemination program and in men representative of the general public. Our goal is to identify the mechanism(s) underlying lead's anti-fertility action.
Key facts
- Study ID
- NCT00012480
- Run by
- National Institute of Environmental Health Sciences (NIEHS)
- People needed
- 400
- Starts
- 2002-08-01
- Expected to finish
- 2007-07-01
- Last updated by the study team
- 2015-04-15
Who can join
Age: 21 and older, up to 55. Sex: male. Healthy volunteers: accepted.
Where it is running
- University of Southern California Women's and Children's Hospital — Los Angeles, California, United States
- North Shore University Hospital — Manhasset, New York, United States
- Copper Hospital and Fertility Testing Laboratory and Sperm Bank — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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