Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer

Completed · Phase 3

Conditions studied: Liver Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which chemotherapy regimen is more effective for liver cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two different chemotherapy regimens in treating patients who have recurrent or unresectable liver cancer.

Key facts

Study ID

NCT00012324

Run by

Eximias Pharmaceutical

Starts

2000-09-01

Expected to finish

2005-11-01

Last updated by the study team

2013-06-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Arizona Clinical Research Center, Incorporated — Tucson, Arizona, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Tower Cancer Research Foundation — Beverly Hills, California, United States
• Scripps Cancer Center at Scripps Clinic — La Jolla, California, United States
• David and Donna Long Center for Cancer Treatment at Sharp Grossmont Hospital — La Mesa, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• California Pacific Medical Center - Pacific Campus — San Francisco, California, United States
• Olive View - UCLA Medical Center Foundation — Sylmar, California, United States
• California Hematology/Oncology Medical Group — Torrance, California, United States
• Helen F. Graham Cancer Center — Newark, Delaware, United States
• Lombardi Cancer Center at Georgetown University Medical Center — Washington D.C., District of Columbia, United States
• Florida Cancer Institute - Bayonet Point — Hudson, Florida, United States
• University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
• Oncology-Hematology Group of South Florida, P.A. — Miami, Florida, United States
• Ocala Research Institute, Incorporated — Ocala, Florida, United States
• Cancer Research Center of Hawaii — Honolulu, Hawaii, United States
• Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago, Illinois, United States
• University of Illinois at Chicago Cancer Center — Chicago, Illinois, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Louisiana Oncology Associates - Lafayette — Lafayette, Louisiana, United States
• Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans — New Orleans, Louisiana, United States
• Alvin and Lois Lapidus Cancer Institute at Sinai Hospital — Baltimore, Maryland, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• Saint Louis University Cancer Center — St Louis, Missouri, United States
• Siteman Cancer Center at Barnes-Jewish Hospital — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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