Chemotherapy and Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Stomach Who Have Undergone Surgery

Completed · Phase 2

Conditions studied: Esophageal Cancer, Gastric Cancer

In brief

RATIONALE: Drugs used in chemotherapy such as cisplatin and paclitaxel use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Cisplatin and paclitaxel may make the tumor cells more sensitive to radiation therapy and may kill any tumor cells remaining after surgery. PURPOSE: Randomized phase II trial to study the effectiveness of cisplatin, paclitaxel, and radiation therapy with or without fluorouracil in treating patients who have stage IB, stage IIB, or stage IIIB stomach cancer that has been removed during surgery.

Key facts

Study ID

NCT00011960

Run by

Radiation Therapy Oncology Group

Starts

2001-05-01

Last updated by the study team

2015-11-17

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Mobile Infirmary Medical Center — Mobile, Alabama, United States
• Providence Alaska Medical Center — Anchorage, Alaska, United States
• Foundation for Cancer Research and Education — Phoenix, Arizona, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Sutter Health Western Division Cancer Research Group — Greenbrae, California, United States
• Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• University of California Davis Cancer Center — Sacramento, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• Memorial Hospital Cancer Center — Colorado Springs, Colorado, United States
• University of Colorado Cancer Center at University of Colorado Health Sciences Center — Denver, Colorado, United States
• Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
• Baptist Hospital of Miami — Miami, Florida, United States
• Alexian Brothers Cancer Care Center — Elk Grove Village, Illinois, United States
• Wendt Regional Cancer Center of Finley Hospital — Dubuque, Iowa, United States
• Cancer Center at Lexington Clinic — Lexington, Kentucky, United States
• Cancer Research Center at Boston Medical Center — Boston, Massachusetts, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• CCOP - Kansas City — Kansas City, Missouri, United States
• Siteman Cancer Center — St Louis, Missouri, United States
• Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha — Omaha, Nebraska, United States
• John F. Kennedy Medical Center — Edison, New Jersey, United States
• Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital — Mount Holly, New Jersey, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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