Pollutant Altered Allergic Responses
Completed
Conditions studied: Allergic Rhinitis, Allergy
In brief
This study is designed to investigate whether exposure to particulate air pollution increases the allergic response to allergens. Research studies suggest that symptoms in individuals with allergies may be aggravated by exposure to particulate air pollution. We sought to experimental determine this by exposing human volunteers to combustion particles, a component of air pollution, and then challenge them with an allergen such as ragweed or oak tree pollen. Using biological tests we can measure whether the allergen response is magnified by prior particulate exposure.
Key facts
- Study ID
- NCT00011440
- Run by
- National Institute of Environmental Health Sciences (NIEHS)
- People needed
- 20
- Starts
- 1998-12-01
- Expected to finish
- 2002-08-01
- Last updated by the study team
- 2006-03-23
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
Where it is running
- Harvard School of Public Health — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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