Lactobacillus Plantarum as Therapy for NK-T Cell Deficiency

Completed · Not applicable

Conditions studied: Diabetes Mellitus

In brief

The etiology of immune-mediated diabetes mellitus (IMD) remains unclear. However, previous studies indicate that autoimmunity may be a result of dysfunction of natural killer T cells (NK-T cells). Newly diagnoses patients with IMD have been shown in our laboratory to have significantly lower NK-T cells than normal controls. Other studies have shown that oral administration of lactobacillus can boost NK-T cell activity in children with HIV without side effects. Our objective is to evaluate the effect of lactobacillus administration on NK-T cell activity in patients with IMD

Key facts

Study ID

NCT00011141

Run by

National Center for Research Resources (NCRR)

Last updated by the study team

2005-06-24

Who can join

Age: 1 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Cornell University — New York, New York, United States

Full record on ClinicalTrials.gov

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