Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach

Completed · Phase 2

Conditions studied: Esophageal Cancer, Gastric Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of combination chemotherapy plus radiation therapy with and without fluorouracil in treating patients who have cancer of the esophagus or stomach.

Key facts

Study ID

NCT00009880

Run by

Radiation Therapy Oncology Group

Starts

2001-04-01

Last updated by the study team

2013-07-19

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Foundation for Cancer Research and Education — Phoenix, Arizona, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Leavey Cancer Center at Northridge Hospital Medical Center — Northridge, California, United States
• University of Florida Shands Cancer Center — Gainesville, Florida, United States
• Baptist-South Miami Regional Cancer Program — Miami, Florida, United States
• CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
• Cancer Research Center of Hawaii — Honolulu, Hawaii, United States
• Methodist Medical Center of Illinois — Peoria, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• Cancer Center at Ball Memorial Hospital — Muncie, Indiana, United States
• Memorial Hospital of South Bend — South Bend, Indiana, United States
• Union Hospital — Terre Haute, Indiana, United States
• Wendt Regional Cancer Center at Finley Hospital — Dubuque, Iowa, United States
• Esther Marie Hatton Cancer Care Center at St. Elizabeth Medical Center — Edgewood, Kentucky, United States
• Tulane Cancer Center at Tulane University Hospital and Clinic — New Orleans, Louisiana, United States
• Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
• CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• CCOP - Kansas City — Kansas City, Missouri, United States
• Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha — Omaha, Nebraska, United States
• Monmouth Medical Center — Long Branch, New Jersey, United States
• Atlantic City Medical Center - Mainland Division — Pomona, New Jersey, United States
• Community Medical Center — Toms River, New Jersey, United States
• Mobile Infirmary Medical Center — Mobile, Alabama, United States

Full record on ClinicalTrials.gov

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