Irinotecan in Treating Children With Refractory or Advanced Solid Tumors Who Are Receiving Anticonvulsants

Completed · Phase 1

Conditions studied: Unspecified Childhood Solid Tumor, Protocol Specific

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of irinotecan in treating children with refractory or advanced solid tumors who are receiving anticonvulsants.

Key facts

Study ID

NCT00008424

Run by

Children's Oncology Group

People needed

7

Starts

2000-10-01

Expected to finish

2006-09-01

Last updated by the study team

2014-05-05

Who can join

Age: 1 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
• University of California San Diego Cancer Center — La Jolla, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• Lucile Packard Children's Hospital at Stanford — Palo Alto, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• Children's Hospital of Denver — Denver, Colorado, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Shands Hospital and Clinics, University of Florida — Gainesville, Florida, United States
• Emory University Hospital - Atlanta — Atlanta, Georgia, United States
• Children's Memorial Hospital, Chicago — Chicago, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
• Boston Floating Hospital Infants and Children — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Mott Children's Hospital — Ann Arbor, Michigan, United States
• Children's Hospital of Michigan — Detroit, Michigan, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Children's Mercy Hospital — Kansas City, Missouri, United States
• Cardinal Glennon Children's Hospital — St Louis, Missouri, United States
• Hackensack University Medical Center — Hackensack, New Jersey, United States
• Roswell Park Cancer Institute — Buffalo, New York, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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