The Identification of Prognostic Factors of Late Stage Disease, Particularly Those That Are Modifiable, That Might Explain the Worsened Prognosis With Colorectal Cancer Among Veterans.
Completed
Conditions studied: Colorectal Cancer
In brief
Colorectal cancer is the second leading cause of cancer death in the United States each year. Approximately one million veterans aged 50 and older will develop colorectal cancer over the remainder of their lives and nearly 433,000 will die from it. Because most cancers are diagnosed after local or regional spread, nearly half of all patients diagnosed with colorectal cancer will die. On a national basis, the relative five year survival with colorectal cancer was estimated at approximately 40% among veterans, substantially lower than SEER estimates in the general population of 61.7% (colon) and 59.3% (rectum). Colorectal cancer is preventable through screening, however and, if diagnosed in an early stage (Dukes' A and B), is curable. This is the first study to examine factors that might explain the worsened prognosis for veterans with colorectal cancer. If modifiable factors such as physician and patient delay in diagnosis, or poverty, explain the increased mortality among veterans, educational programs and interventions that improve the process of care associated with screening and diagnosis can be instituted.
Key facts
- Study ID
- NCT00007618
- Run by
- US Department of Veterans Affairs
- Starts
- 1998-01-01
- Last updated by the study team
- 2011-02-03
Who can join
Age: 40 and older, up to 79. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Colorectal cancer patients at the 14 participating sites
Where it is running
- Durham VA Medical Center HSR&D COE — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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