Dexamethasone Treatment for Congenital Heart Block (CHB) in Newborns With Lupus

Completed · Not applicable

Conditions studied: Congenital Heart Block, Neonatal Lupus, Atrioventricular Nodal Dysfunction, Myocardial Injury

In brief

Some newborns are born with congenital heart block (CHB), a condition occurring in babies with neonatal lupus. The first part of the study will test the effectiveness of fluorinated steroids, including dexamethasone, in improving the heart function and general health of newborns who have auto-antibody-associated CHB. The second part of this study will use ultrasound and heart monitoring to observe high-risk pregnant women and their fetuses during the third trimester of pregnancy.

Key facts

Study ID

NCT00007358

Run by

NYU Langone Health

People needed

150

Starts

2000-10-01

Expected to finish

2008-10-01

Last updated by the study team

2016-03-11

Who can join

Age: 16 and older, up to 50. Sex: female. Healthy volunteers: accepted.

Where it is running

• Yale University Medical Center — New Haven, Connecticut, United States
• St. Barnabas Medical Center — Livingston, New Jersey, United States
• Hospital for Joint Diseases — New York, New York, United States
• New York University Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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