Muscle Strengthening Device for Knee Osteoarthritis
Completed · Phase 2
Conditions studied: Osteoarthritis
In brief
Studies have shown that isometric strengthening helps people with osteoarthritis of the knee. Isometric strengthening is muscle-strengthening exercise without movement, in which a person applies a force against a resistant object--for example, pushing against a brick wall. This study will test the effectiveness of a portable isometric exercise device for home use that guides a person through an exercise program using various forms of feedback. We will look at whether people exercising with the device achieve better outcomes (results) in pain, stiffness, strength, and functional measures compared to people who do not use the device or people exercising according to printed material from arthritis organizations.
Key facts
- Study ID
- NCT00007241
- Run by
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- People needed
- 92
- Starts
- 2001-09-01
- Expected to finish
- 2002-07-01
- Last updated by the study team
- 2007-01-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Able to give conformed consent.
- Age > 18.
- Pain symptoms provoked by activity in the more symptomatic knee of between (and inclusive of) 3/10 and 8/10 on a verbal analog scale.
You may not qualify if…
- Participation in a strengthening program of the knees in the past month.
- Uncontrolled or functionally limiting cardiac disease.
- Uncontrolled hypertension.
- Severe peripheral neuropathy (i.e., insensate to the Simmes 5.07 monofilament).
- Knee flexion contracture greater than 10 degrees.
- Intra-articular steroids in the past 3 months, or hyaluronic acid in the last 9 months.
- Poor health that would impair compliance or assessment.
- Arthroscopy of either knee in the past six months.
- Lateral instability of > 15 degrees, or posterio-anterior instability of greater than 1 cm.
- Knee pain due to pes anserine bursitis.
- Active fibromyalgia.
- Active alcohol or substance abuse.
- Arthritis other than osteoarthritis in the more symptomatic knee.
- Pregnancy.
- History of cancer (other than skin cancer) not in remission.
- Symptomatic spine, hip, ankle, or foot disease other than osteoarthritis that would interfere with assessment of the knee.
Where it is running
- Clinical Research Consultants, Inc. — Trumbull, Connecticut, United States
- Radiant Research, Inc. — Moorestown, New Jersey, United States
- Rochester Clinical Research, Inc. — Rochester, New York, United States
- Preventive Medical Technologies, Inc. — Philadelphia, Pennsylvania, United States
- Radiant Research, Inc. — Wyomissing, Pennsylvania, United States
- Omega Medical Research — Warwick, Rhode Island, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.