Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor
Completed · Phase 3
Conditions studied: Sarcoma
In brief
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which chemotherapy regimen combined with radiation therapy and/or surgery is more effective in treating Ewing's sarcoma or primitive neuroectodermal tumor. PURPOSE: Randomized phase III trial to compare the effectiveness of different chemotherapy regimens combined with radiation therapy and/or surgery in treating patients who have Ewing's sarcoma or primitive neuroectodermal tumor.
Key facts
- Study ID
- NCT00006734
- Run by
- Children's Oncology Group
- People needed
- 587
- Starts
- 2001-05-01
- Expected to finish
- 2023-06-30
- Last updated by the study team
- 2023-08-03
Who can join
Age: any, up to 50. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of South Alabama Cancer Research Institute — Mobile, Alabama, United States
- Phoenix Children's Hospital — Phoenix, Arizona, United States
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Southern California Permanente Medical Group — Downey, California, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
- Jonathan Jaques Children's Cancer Center at Miller Children's Hospital — Long Beach, California, United States
- Children's Hospital Los Angeles — Los Angeles, California, United States
- Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center at UCLA — Los Angeles, California, United States
- Children's Hospital Central California — Madera, California, United States
- Children's Hospital and Research Center at Oakland — Oakland, California, United States
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
- Children's Hospital of Orange County — Orange, California, United States
- Lucile Packard Children's Hospital at Stanford University Medical Center — Palo Alto, California, United States
- Sutter Cancer Center — Sacramento, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- Kaiser Permanente Medical Center - Sacramento — Sacramento, California, United States
- Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego — San Diego, California, United States
- Children's Hospital and Health Center - San Diego — San Diego, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Santa Barbara Cottage Hospital — Santa Barbara, California, United States
- Comprehensive Cancer Center at University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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