S0016 Combination Chemotherapy With Monoclonal Antibody Therapy in Newly Diagnosed Non-Hodgkin's Lymphoma
Completed · Phase 3
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies can locate tumor cells and either kill them or deliver radioactive tumor-killing substances to them without harming normal cells. It is not yet known which monoclonal antibody plus combination chemotherapy regimen is more effective in treating non-Hodgkin's lymphoma. PURPOSE: This randomized phase III trial is comparing 2 different monoclonal antibodies given together with combination chemotherapy to see how well they work in treating patients with newly-diagnosed non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00006721
- Run by
- SWOG Cancer Research Network
- People needed
- 571
- Starts
- 2001-03-01
- Expected to finish
- 2025-12-01
- Last updated by the study team
- 2026-03-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital — Fairbanks, Alaska, United States
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California, United States
- Peninsula Medical Center — Burlingame, California, United States
- Marin Cancer Institute at Marin General Hospital — Greenbrae, California, United States
- Sutter Health - Western Division Cancer Research Group — Greenbrae, California, United States
- Desert Regional Medical Center Comprehensive Cancer Center — Palm Springs, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- California Pacific Medical Center - California Campus — San Francisco, California, United States
- Stanford Cancer Center — Stanford, California, United States
- Sutter Solano Medical Center — Vallejo, California, United States
- Helen and Harry Gray Cancer Center at Hartford Hospital — Hartford, Connecticut, United States
- Lombardi Comprehensive Cancer Center at Georgetown University Medical Center — Washington D.C., District of Columbia, United States
- Center for Cancer Care and Research at Watson Clinic, LLP — Lakeland, Florida, United States
- Sacred Heart Cancer Center at Sacred Heart Hospital — Pensacola, Florida, United States
- West Florida Cancer Institute at West Florida Hospital - Pensacola — Pensacola, Florida, United States
- Piedmont Hospital — Atlanta, Georgia, United States
- Northside Hospital Cancer Center — Atlanta, Georgia, United States
- Saint Joseph's Hospital of Atlanta — Atlanta, Georgia, United States
- CCOP - Atlanta Regional — Atlanta, Georgia, United States
- WellStar Cobb Hospital — Austell, Georgia, United States
- Charles B. Eberhart Cancer Center at DeKalb Medical Center — Decatur, Georgia, United States
- Dwight David Eisenhower Army Medical Center — Fort Gordon, Georgia, United States
- Alaska Regional Hospital Cancer Center — Anchorage, Alaska, United States
Full record on ClinicalTrials.gov
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