S0019 Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Stopped early · Phase 3

Conditions studied: Lymphoma

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. It is not yet known whether combination chemotherapy is more effective with or without rituximab for non-Hodgkin's lymphoma. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without rituximab in treating patients who have relapsed or refractory non-Hodgkin's lymphoma.

Key facts

Study ID

NCT00006708

Run by

SWOG Cancer Research Network

People needed

7

Starts

2000-10-01

Expected to finish

2006-11-01

Last updated by the study team

2013-04-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• CCOP - Greater Phoenix — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Phoenix (Hayden) — Phoenix, Arizona, United States
• Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Veterans Affairs Medical Center - Little Rock (McClellan) — Little Rock, Arkansas, United States
• Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• David Grant Medical Center — Travis Air Force Base, California, United States
• University of Colorado Cancer Center — Denver, Colorado, United States
• Veterans Affairs Medical Center - Denver — Denver, Colorado, United States
• CCOP - Atlanta Regional — Atlanta, Georgia, United States
• Dwight David Eisenhower Army Medical Center — Fort Gordon, Georgia, United States
• Cancer Research Center of Hawaii — Honolulu, Hawaii, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) — Hines, Illinois, United States
• Loyola University Medical Center — Maywood, Illinois, United States
• MBCCOP - Gulf Coast — Mobile, Alabama, United States

Full record on ClinicalTrials.gov

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