Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease

Completed · Phase 2

Conditions studied: Alzheimer Disease

In brief

The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.

Key facts

Study ID

NCT00006399

Run by

National Center for Research Resources (NCRR)

People needed

45

Starts

1999-09-01

Expected to finish

2004-03-01

Last updated by the study team

2009-01-15

Who can join

Age: 45 and older, up to 85. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Normal volunteers and women with mild Alzheimer's disease:
• Non-smoker
• No use of Hormone Replacement Therapy for at least one year
• No menses for at least one year
• Normal mammogram within the last year
• minimum age is 45 for patients with Alzheimer's disease; 50 for normal volunteers
• Maximum age is 85 for patients with Alzheimer's disease; there is no maximum age for normal volunteers.

You may not qualify if…

• Women who are currently taking estrogen therapy.
• Women who are smokers.
• Women who have had breast cancer.

Where it is running

• Clinical Neuroscience Research Unit, University of Vermont — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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