Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum
Completed · Phase 2
Conditions studied: Colorectal Cancer
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which regimen of radiation therapy plus chemotherapy is more effective for rectal cancer. PURPOSE: Randomized phase II trial to compare two regimens of radiation therapy plus chemotherapy followed by surgery in treating patients who have locally advanced cancer of the rectum.
Key facts
- Study ID
- NCT00006366
- Run by
- Radiation Therapy Oncology Group
- Starts
- 2001-02-01
- Last updated by the study team
- 2020-10-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Comprehensive Cancer Institute of Huntsville — Huntsville, Alabama, United States
- Huntsville Hospital System — Huntsville, Alabama, United States
- MBCCOP - Gulf Coast — Mobile, Alabama, United States
- Alabama Oncology, LLC — Montgomery, Alabama, United States
- Radiation Oncology Associates of West Alabama — Tuscaloosa, Alabama, United States
- Foundation for Cancer Research and Education — Phoenix, Arizona, United States
- Mount Diablo Medical Center — Concord, California, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Saint Agnes Cancer Center — Fresno, California, United States
- California Cancer Center — Fresno, California, United States
- Sutter Health West Cancer Research Group — Greenbrae, California, United States
- Loma Linda University Medical Center — Loma Linda, California, United States
- Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Huntington Cancer Center — Pasadena, California, United States
- Cancer Care Center — Pomona, California, United States
- Radiation Oncology Center - Sacramento — Sacramento, California, United States
- Radiation Medical Group, Inc. — San Diego, California, United States
- UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
- O'Connor Hospital — San Jose, California, United States
- CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
- David Grant Medical Center — Travis Air Force Base, California, United States
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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