Oral Manifestations of Aplastic Anemia

Completed

Conditions studied: Aplastic Anemia

In brief

The purposes of this study are threefold: 1) to evaluate the prevalence and risks of oral complications in patients with aplastic anemia; 2) to evaluate if oral problems in these patients can predict their response to treatment; and 3) to review complications of dental treatment in these patients in order to establish treatment guidelines. This study will be performed through a review of medical charts of 79 patients with aplastic anemia and 67 patients with schizophrenia who were treated at the National Institutes of Health Dental Clinic between 1993 and 1999. The schizophrenia patients will serve as a control population. Demographic, clinical and radiographic information will be collected for all patients. Additional data collected only for aplastic anemia patients will include medical therapy, disease duration, blood cell counts, oral problems that developed during treatment and treatment response.

Key facts

Study ID

NCT00006300

Run by

National Institute of Dental and Craniofacial Research (NIDCR)

People needed

146

Starts

2000-04-01

Expected to finish

2002-04-01

Last updated by the study team

2008-03-04

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Cases: All aplastic anemia patients evaluated at the NIH dental clinic for consultation between 1993-1999.
• Controls: All schizophrenic patients evaluated at the NIH dental clinic for consultation between 1993-1999.

You may not qualify if…

• Patients without the diagnosis of aplastic anemia for cases or schizophrenia for the controls.

Where it is running

• National Institute of Dental And Craniofacial Research (NIDCR) — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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