Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Completed · Phase 2

Conditions studied: Brain and Central Nervous System Tumors

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug or combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by radiation therapy in treating patients who have surgically resected, newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor, or incompletely resected ependymoma.

Key facts

Study ID

NCT00006258

Run by

Children's Hospital Los Angeles

Starts

1997-11-01

Expected to finish

2005-01-01

Last updated by the study team

2013-07-18

Who can join

Age: 10 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Children's Hospital Los Angeles — Los Angeles, California, United States
• Geisinger Medical Center — Danville, Pennsylvania, United States
• Tom Baker Cancer Centre - Calgary — Calgary, Alberta, Canada

Full record on ClinicalTrials.gov

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