Fludarabine and Cyclophosphamide Followed by Peripheral Stem Cell Transplant in Treating Patients With Leukemia or Lymphoma
Completed · Phase 2
Conditions studied: Leukemia, Lymphoma
In brief
RATIONALE: Giving chemotherapy drugs, such as fludarabine and cyclophosphamide, before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. PURPOSE: This phase II trial is studying how well fludarabine and cyclophosphamide followed by peripheral stem cell transplant works in treating patients with leukemia or lymphoma.
Key facts
- Study ID
- NCT00006252
- Run by
- Cancer and Leukemia Group B
- People needed
- 47
- Starts
- 2001-02-01
- Expected to finish
- 2011-10-01
- Last updated by the study team
- 2016-07-18
Who can join
Age: any, up to 69. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Veterans Affairs Medical Center - San Diego — San Diego, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- St. Francis Hospital — Wilmington, Delaware, United States
- Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
- Union Hospital Cancer Center at Union Hospital — Elkton MD, Maryland, United States
- UMASS Memorial Cancer Center - University Campus — Worcester, Massachusetts, United States
- Cancer Institute of New Jersey at the Cooper University Hospital - Voorhees — Voorhees Township, New Jersey, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Elmhurst Hospital Center — Elmhurst, New York, United States
- Queens Cancer Center of Queens Hospital — Jamaica, New York, United States
- Mount Sinai Medical Center — New York, New York, United States
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
- Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina, United States
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University — Columbus, Ohio, United States
- Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital — Pittsburgh, Pennsylvania, United States
- Massey Cancer Center at Virginia Commonwealth University — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
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