Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients

Completed · Not applicable

Conditions studied: Hip Fractures, Muscular Atrophy

In brief

Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline. The declines in muscle mass associated with aging may be related to alterations in specific kinds of growth factors in the muscle. Elderly hip fracture patients often have significant decreases in muscle mass. The purpose of this study is to investigate whether an exercise program can induce changes in muscle growth factors that are associated with increases in muscle mass and strength in elderly hip fracture patients.

Key facts

Study ID

NCT00006194

Run by

National Center for Research Resources (NCRR)

Last updated by the study team

2005-06-24

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Enrollment in HSC protocol #97-0695 "Rehabilitation Intensification Post Hip Fracture"
• Community-dwelling
• Hip fracture within 16 weeks of the screening assessment for protocol 97-0695
• Persistent mobility and/or ADL impairments, but independent in ambulation
• Modified Physical Performance Test (PPT) score between 12 and 28

Where it is running

• Washington University — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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