Effectiveness of Adding Remune to Your Current Anti-HIV Drug Combination
Stopped early · Phase 1
Conditions studied: HIV Infections
In brief
The purpose of this study is to see if giving a vaccine (Remune) is effective in HIV-positive patients who are also taking anti-HIV therapy. Regular treatment of HIV-positive patients with anti-HIV drugs slows the multiplication of the HIV virus in the body. A vaccine called Remune works to stop the virus infection by "boosting" the body's immune cell defense against the HIV virus before the virus enters cells. It also blocks the virus from entering the cells. This study will see whether Remune will improve the immune cell natural defense in patients who are also taking anti-HIV drugs.
Key facts
- Study ID
- NCT00006153
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 45
- Last updated by the study team
- 2008-07-30
Who can join
Age: 16 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients may be eligible for this study if they:
- Are HIV-positive and started anti-HIV drugs soon after tests showed the presence of HIV.
- Have been on an anti-HIV drug combination that includes a protease inhibitor for at least 3 months but no longer than 12 months.
- Have 2 consecutive viral loads of less than 50 copies/ml, at least 30 days apart, within 90 days of study entry.
- Are at least 16 years old (consent of parent or guardian required if under 18 years).
- Agree to practice abstinence or use effective methods of birth control during the study.
You may not qualify if…
- Patients will not be eligible for this study if they:
- Are pregnant or breast-feeding.
- Currently abuse alcohol or drugs.
- Are currently being treated for some types of cancer.
- Have any illness or condition that might interfere with the study or put them at risk.
- Have received a vaccination 6 weeks before study entry.
- Have previously received Remune.
- Are taking medications that affect the immune system within 30 days of study entry.
Where it is running
- Joanne Santangelo — San Diego, California, United States
Full record on ClinicalTrials.gov
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