A Study of HIV-Disease Development in Aging

Completed · Phase 2

Conditions studied: HIV Infections

In brief

The purpose of this study is to better understand the relationship between age and HIV disease progression. This study will explore the possible relationship between age and HIV disease progression. Older age is an important risk factor for faster disease development, but older people may respond better to combination drug therapy. This relationship needs to be understood better.

Key facts

Study ID

NCT00006144

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

90

Starts

2000-10-01

Expected to finish

2005-04-01

Last updated by the study team

2021-11-01

Who can join

Age: 13 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients may be eligible for this study if they:
• Are HIV-positive.
• Are between 13 and 30 years old (need consent of parent or guardian if under 18), or are more than 44 years of age.
• Have a viral load of more than 2000 copies/ml within 60 days of study entry.
• Have a CD4 cell count of less than 600 cells/mm3 within 60 days of study entry. (This reflects a change in the CD4 cell count requirement.)
• Agree to use effective methods of birth control (such as condoms) during and for 12 weeks after the study.

You may not qualify if…

• Patients will not be eligible for this study if they:
• Are pregnant or breast-feeding.
• Have an AIDS-related cancer (except Kaposi's sarcoma) requiring chemotherapy.
• Have hepatitis within 30 days of study entry.
• Have diarrhea (more than 3 liquid stools/day for at least 14 days) within 30 days of study entry.
• Are receiving chemotherapy or radiation treatment.
• Have taken antiretroviral drugs for more than 14 days.
• Have received an HIV vaccine within 30 days of study.
• Have a serious illness or infection within 14 days of the study.
• Have other serious conditions that might interfere with study participation.
• Have taken or plan to take certain other drugs that might affect the study results.

Where it is running

• USC CRS — Los Angeles, California, United States
• Stanford CRS — Palo Alto, California, United States
• Ucsf Aids Crs — San Francisco, California, United States
• Santa Clara Valley Med. Ctr. — San Jose, California, United States
• San Mateo County AIDS Program — San Mateo, California, United States
• Marin County Dept. of Health & Human Services, HIV/AIDS Program & Specialty Clinic — San Rafael, California, United States
• University of Colorado Hospital CRS — Aurora, Colorado, United States
• Univ. of Miami AIDS CRS — Miami, Florida, United States
• Queens Med. Ctr. — Honolulu, Hawaii, United States
• Univ. of Hawaii at Manoa, Leahi Hosp. — Honolulu, Hawaii, United States
• Northwestern University CRS — Chicago, Illinois, United States
• Rush Univ. Med. Ctr. ACTG CRS — Chicago, Illinois, United States
• Indiana Univ. School of Medicine, Infectious Disease Research Clinic — Indianapolis, Indiana, United States
• Indiana Univ. School of Medicine, Wishard Memorial — Indianapolis, Indiana, United States
• Methodist Hosp. of Indiana — Indianapolis, Indiana, United States
• Johns Hopkins Adult AIDS CRS — Baltimore, Maryland, United States
• Massachusetts General Hospital ACTG CRS — Boston, Massachusetts, United States
• Bmc Actg Crs — Boston, Massachusetts, United States
• Brigham and Women's Hosp. ACTG CRS — Boston, Massachusetts, United States
• Beth Israel Deaconess Med. Ctr., ACTG CRS — Boston, Massachusetts, United States
• SSTAR, Family Healthcare Ctr. — Fall River, Massachusetts, United States
• University of Minnesota, ACTU — Minneapolis, Minnesota, United States
• Washington U CRS — St Louis, Missouri, United States
• Beth Israel Med. Ctr., ACTU — New York, New York, United States
• NY Univ. HIV/AIDS CRS — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.