Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Completed · Phase 1

Conditions studied: Unspecified Childhood Solid Tumor, Protocol Specific

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of vincristine plus irinotecan in treating children who have solid tumors that have not responded to previous therapy.

Key facts

Study ID

NCT00006095

Run by

Children's Oncology Group

People needed

20

Starts

2000-07-01

Expected to finish

2005-09-01

Last updated by the study team

2014-02-21

Who can join

Age: 1 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• Children's Mercy Hospital — Kansas City, Missouri, United States
• NYU School of Medicine's Kaplan Comprehensive Cancer Center — New York, New York, United States
• Memorial Sloan-Kettering Cancer Center — New York, New York, United States
• Mount Sinai School of Medicine — New York, New York, United States
• Children's Hospital Medical Center - Cincinnati — Cincinnati, Ohio, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
• Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States
• University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
• Children's Hospital and Regional Medical Center - Seattle — Seattle, Washington, United States
• University of Wisconsin Comprehensive Cancer Center — Madison, Wisconsin, United States
• Princess Margaret Hospital for Children — Perth, Western Australia, Australia

Full record on ClinicalTrials.gov

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