Diagnostic Study of Quantitative Imaging and Spectroscopy in Patients With Multiple Sclerosis

Status unconfirmed

Conditions studied: Multiple Sclerosis

In brief

OBJECTIVES: I. Determine by quantitative magnetic resonance imaging measurements the change in the total volume of brain parenchyma as well as its gray and white matter, T2 and enhanced T1 lesion volume, and the magnetization transfer ratio histogram parameters, and correlate these measurements with clinical measures of disability in patients with multiple sclerosis. II. Measure the quantity of whole brain N-acetylaspartate in patients with multiple sclerosis and compare these values to those from age matched controls. III. Determine the correlation between specific neuropsychological tests which assess global cognitive functioning and the quantitative measurements taken in these patients in this study.

Key facts

Study ID

NCT00006060

Run by

National Center for Research Resources (NCRR)

People needed

100

Starts

1999-04-01

Last updated by the study team

2009-03-12

Who can join

Age: 20 and older, up to 70. Sex: any. Healthy volunteers: accepted.

Where it is running

• New York University Medical Center — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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