Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia

Status unconfirmed · Phase 3

Conditions studied: Leukemia

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. It is not yet known if chemotherapy is more effective with or without monoclonal antibody therapy for acute myelogenous leukemia. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without monoclonal antibody therapy in treating patients who have refractory or relapsed acute myelogenous leukemia.

Key facts

Study ID

NCT00006045

Run by

Facet Biotech

Starts

2000-03-01

Last updated by the study team

2013-11-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Beckman Research Institute, City of Hope — Los Angeles, California, United States
• St. Joseph Hospital - Orange — Orange, California, United States
• Sutter Cancer Center — Sacramento, California, United States
• University of California Davis Cancer Center — Sacramento, California, United States
• Sidney Kimmel Cancer Center — San Diego, California, United States
• Washington Cancer Institute — Washington D.C., District of Columbia, United States
• Emory Clinic — Atlanta, Georgia, United States
• University of Illinois at Chicago — Chicago, Illinois, United States
• Loyola University Medical Center — Maywood, Illinois, United States
• University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
• Louisiana State University School of Medicine — Shreveport, Louisiana, United States
• Johns Hopkins Oncology Center — Baltimore, Maryland, United States
• New England Medical Center Hospital — Boston, Massachusetts, United States
• Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• West Michigan Cancer Center — Kalamazoo, Michigan, United States
• North Mississippi Hematology and Oncology Associates, Ltd. — Tupelo, Mississippi, United States
• Washington University Barnard Cancer Center — St Louis, Missouri, United States
• Nevada Cancer Center — Las Vegas, Nevada, United States
• Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
• Roswell Park Cancer Institute — Buffalo, New York, United States
• North Shore University Hospital — Manhasset, New York, United States
• USC/Norris Comprehensive Cancer Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.