Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer
Stopped early · Phase 2
Conditions studied: Colorectal Cancer
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: This phase II trial is studying combination chemotherapy plus trastuzumab to see how well it works in treating patients with advanced, recurrent, or metastatic colorectal cancer.
Key facts
- Study ID
- NCT00006015
- Run by
- National Cancer Institute (NCI)
- People needed
- 26
- Starts
- 2000-05-01
- Expected to finish
- 2003-02-01
- Last updated by the study team
- 2013-05-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States
- University of California San Diego Cancer Center — La Jolla, California, United States
- Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
- UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
- CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
- Lombardi Cancer Center — Washington D.C., District of Columbia, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Hematology Oncology Associates of the Quad Cities — Bettendorf, Iowa, United States
- Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
- Veterans Affairs Medical Center - Togus — Togus, Maine, United States
- Marlene and Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
- Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- University of Massachusetts Memorial Medical Center - University Campus — Worcester, Massachusetts, United States
- Veterans Affairs Medical Center - Minneapolis — Minneapolis, Minnesota, United States
- University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
- Veterans Affairs Medical Center - Columbia (Truman Memorial) — Columbia, Missouri, United States
- Ellis Fischel Cancer Center - Columbia — Columbia, Missouri, United States
- Barnes-Jewish Hospital — St Louis, Missouri, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- CCOP - Southern Nevada Cancer Research Foundation — Las Vegas, Nevada, United States
- Norris Cotton Cancer Center — Lebanon, New Hampshire, United States
Full record on ClinicalTrials.gov
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