Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

Status unconfirmed · Phase 2

Conditions studied: Lymphoma

In brief

RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with rituximab may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of rituximab plus combination chemotherapy in treating patients who have intermediate-grade or high-grade non-Hodgkin's lymphoma.

Key facts

Study ID

NCT00005959

Run by

Amgen

Starts

1999-12-01

Last updated by the study team

2013-12-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Montgomery Cancer Center — Montgomery, Alabama, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• Cancer and Blood Institute of the Desert — Rancho Mirage, California, United States
• Southeast Florida Hematology-Oncology Group — Fort Lauderdale, Florida, United States
• Oncology-Hematology Group of South Florida — Miami, Florida, United States
• Mount Sinai Comprehensive Cancer Center — Miami Beach, Florida, United States
• Hematology-Oncology Associates, PA — Pensacola, Florida, United States
• Hutchinson Clinic, P.A. — Hutchinson, Kansas, United States
• Hematology/Oncology Care Inc. — Crestview Hills, Kentucky, United States
• Maine Center for Cancer Medicine and Blood Disorders — Scarborough, Maine, United States
• Associates in Oncology and Hematology — Rockville, Maryland, United States
• North Shore Cancer Center — Peabody, Massachusetts, United States
• Henry Ford Hospital — Detroit, Michigan, United States
• Lakeland Medical Center - St. Joseph — Saint Joseph, Michigan, United States
• Bond Clinic — Rolla, Missouri, United States
• Midwest Hematology Oncology Consultants, Ltd. — St Louis, Missouri, United States
• Hematology Oncology Associates — Morristown, New Jersey, United States
• New Mexico Oncology-Hematology — Albuquerque, New Mexico, United States
• HemOnCare, P.C. — Brooklyn, New York, United States
• Our Lady of Mercy Medical Center — The Bronx, New York, United States
• N.W. Carolina Oncology & Hematology, P.A. — Hickory, North Carolina, United States
• Oncology/Hematology Care, Inc. — Cincinnati, Ohio, United States
• University of Tennessee, Memphis — Memphis, Tennessee, United States
• Intermountain Hematology/Oncology Associates, Inc. — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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