Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
Completed · Phase 3
Conditions studied: Leukemia
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating childhood acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is comparing different combination chemotherapy regimens to see how well they work in treating children with acute lymphoblastic leukemia.
Key facts
- Study ID
- NCT00005945
- Run by
- Children's Oncology Group
- People needed
- 3054
- Starts
- 2000-06-01
- Expected to finish
- 2008-06-01
- Last updated by the study team
- 2016-02-23
Who can join
Age: 1 and older, up to 9. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Southern California Permanente Medical Group — Downey, California, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
- Children's Hospital Los Angeles — Los Angeles, California, United States
- Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center — Los Angeles, California, United States
- Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
- Children's Hospital Central California — Madera, California, United States
- Children's Hospital and Research Center at Oakland — Oakland, California, United States
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
- Children's Hospital of Orange County — Orange, California, United States
- Kaiser Permanente Medical Center - Sacramento — Sacramento, California, United States
- Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego — San Diego, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Santa Barbara Cottage Hospital — Santa Barbara, California, United States
- Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
- General Robert Huyser Cancer Center at David Grant Medical Center — Travis Air Force Base, California, United States
- Children's Hospital Cancer Center — Denver, Colorado, United States
- Presbyterian - St. Luke's Medical Center — Denver, Colorado, United States
- Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center — Farmington, Connecticut, United States
- Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
- Alfred I. duPont Hospital for Children — Wilmington, Delaware, United States
- Lombardi Cancer Center at Georgetown University Medical Center — Washington D.C., District of Columbia, United States
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus — Atlanta, Georgia, United States
- Phoenix Children's Hospital — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
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