Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Completed · Phase 3

Conditions studied: Metastatic Cancer

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as RSR13 may make tumor cells more sensitive to radiation therapy. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy to the brain with or without RSR13 in treating patients who have brain metastases.

Key facts

Study ID

NCT00005887

Run by

Spectrum Pharmaceuticals, Inc

Starts

2000-02-01

Expected to finish

2003-01-01

Last updated by the study team

2021-08-23

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Arizona Cancer Center — Tucson, Arizona, United States
• Alta Bates Comprehensive Cancer Center — Berkeley, California, United States
• California Cancer Care, Inc. — Greenbrae, California, United States
• Scripps Green Hospital & Scripps Clinic — La Jolla, California, United States
• Tower Hematology Oncology Medical Group — Los Angeles, California, United States
• University of Colorado Cancer Center — Denver, Colorado, United States
• Comprehensive Cancer Care Specialists of Boca Raton — Boca Raton, Florida, United States
• Citrus Memorial Hospital — Inverness, Florida, United States
• Decatur Memorial Hospital Cancer Care Institute — Decatur, Illinois, United States
• Ochsner Clinic — New Orleans, Louisiana, United States
• Harbor Hospital Center — Baltimore, Maryland, United States
• St. Agnes Healthcare — Baltimore, Maryland, United States
• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
• Lahey Clinic - Burlington — Burlington, Massachusetts, United States
• University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
• Cooper Hospital/University Medical Center — Camden, New Jersey, United States
• Monmouth Medical Center — Long Branch, New Jersey, United States
• East Coast Radiation Oncology — Toms River, New Jersey, United States
• Millard Fillmore Hospital — Buffalo, New York, United States
• State University of New York - Upstate Medical University — Syracuse, New York, United States
• Comprehensive Cancer Center at Wake Forest University — Winston-Salem, North Carolina, United States
• Bismarck Cancer Center — Bismarck, North Dakota, United States
• Akron General Medical Center — Akron, Ohio, United States
• Akron City Hospital — Akron, Ohio, United States
• St. Joseph's Hospital and Medical Center — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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