Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer
Completed · Phase 1
Conditions studied: Breast Cancer, Ovarian Cancer, Unspecified Adult Solid Tumor, Protocol Specific
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of BMS-247550 in treating patients who have metastatic, recurrent, or locally advanced, ovarian cancer, breast cancer, or metastatic or unresectable solid tumors.
Key facts
- Study ID
- NCT00005807
- Run by
- Albert Einstein College of Medicine
- People needed
- 40
- Starts
- 2000-07-01
- Expected to finish
- 2004-08-01
- Last updated by the study team
- 2018-10-09
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Histologically or cytologically confirmed metastatic or unresectable solid malignancy for which no standard or curative therapies exist or are no longer effective
- Metastatic, recurrent, or locally advanced breast, ovarian, or other cancer
- Hemoglobin at least 9.0 g/dL
- WBC at least 3,000/mm3
- Absolute neutrophil count at least 1,500/mm3
- Platelet count at least 100,000/mm3
- Bilirubin normal
- AST/ALT no greater than 3 times upper limit of normal
- Gilbert's syndrome allowed
- Creatinine no greater than 2 mg/dL
You may not qualify if…
- symptomatic congestive heart failure
- unstable angina pectoris
- cardiac arrhythmia
- grade 2 or greater clinical neuropathy
- prior allergy or hypersensitivity reaction (grade 2 or greater) to prior paclitaxel or other therapy containing Cremophor EL
- allergy or intolerance to steroids, diphenhydramine, cimetidine, or ranitidine
- uncontrolled concurrent illness
- active infection
- pregnant or nursing
- other concurrent anticancer therapies or commercial agents
- other concurrent investigational agents
- other concurrent highly active antiretroviral therapy for HIV-positive patients
Where it is running
- NYU School of Medicine's Kaplan Comprehensive Cancer Center — New York, New York, United States
- Albert Einstein Clinical Cancer Center — The Bronx, New York, United States
Full record on ClinicalTrials.gov
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