Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
Completed · Phase 1
Conditions studied: Bone Marrow Suppression, Brain and Central Nervous System Tumors, Drug/Agent Toxicity by Tissue/Organ
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Inserting a specific gene into a person's peripheral stem cells may improve the body's ability to fight cancer or make the cancer more sensitive to chemotherapy. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus gene therapy in treating patients who have CNS tumors.
Key facts
- Study ID
- NCT00005796
- Run by
- Indiana University
- People needed
- 10
- Starts
- 2000-02-01
- Expected to finish
- 2011-12-01
- Last updated by the study team
- 2015-03-25
Who can join
Age: 5 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Indiana University Cancer Center — Indianapolis, Indiana, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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