Blood Factors and Diabetic Retinopathy
Completed
Conditions studied: Diabetic Retinopathy
In brief
This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy. Patients age 10 years and older with diabetes mellitus and diabetic retinopathy may be eligible for this study. Those enrolled will represent a range of diabetic retinopathy from minimal to severe. Participants will undergo the following procedures: * medical history * thorough eye examination * photographs of the eye * blood tests to measure blood lipids (cholesterol and triglycerides) and serum creatinine (for kidney function) * blood tests to measure levels of blood factors (cell adhesion molecules, chemokines and vascular endothelial growth factor) that may be related to the progression of diabetic retinopathy * blood pressure measurement * urinalysis This study may lead to a better understanding of how diabetic retinopathy develops and progresses.
Key facts
- Study ID
- NCT00005761
- Run by
- National Eye Institute (NEI)
- People needed
- 173
- Starts
- 2000-05-23
- Expected to finish
- 2010-12-07
- Last updated by the study team
- 2017-07-02
Who can join
Age: 10 and older. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- Neither volunteers nor participants will be eligible if they:
- Are under the age of 10.
- Have severe systemic disease(s) that compromise our ability to obtain an adequate examination.
- Have any of the following ocular characteristics or conditions in both eyes:
- Opacities of the ocular media, limitations or pupillary dilation or any other problems sufficient to preclude good, quality stereo fundus photographs.
- Ocular disease which confounds assessment of diabetic retinopathy such as advanced age-related macular degeneration, central serous choroidopathy, optic atrophy, retinal vein occlusion, active uveitis, significant explained or unexplained visual field loss, or any other type of retinopathy or retinal degeneration.
- Chronic requirement for any ocular medication for other diseases, such as glaucoma.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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