Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia

Completed · Phase 3

Conditions studied: Leukemia

In brief

RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective for acute lymphoblastic leukemia. PURPOSE: Phase III trial to determine the effectiveness of combination chemotherapy in treating children who have newly diagnosed acute lymphoblastic leukemia.

Key facts

Study ID

NCT00005603

Run by

Children's Oncology Group

People needed

276

Starts

2000-03-01

Last updated by the study team

2014-02-20

Who can join

Age: 1 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Children's Hospital Los Angeles — Los Angeles, California, United States
• Lucile Packard Children's Hospital at Stanford — Palo Alto, California, United States
• UCSF Comprehensive Cancer Center — San Francisco, California, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Saint Jude Midwest Affiliate — Peoria, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Herbert Irving Comprehensive Cancer Center — New York, New York, United States
• State University of New York - Upstate Medical University — Syracuse, New York, United States
• Albert Einstein Clinical Cancer Center — The Bronx, New York, United States
• Children's Hospital Medical Center - Cincinnati — Cincinnati, Ohio, United States
• Doernbecher Children's Hospital — Portland, Oregon, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
• Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States
• University of Texas Medical Branch — Galveston, Texas, United States
• University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
• Baylor College of Medicine — Houston, Texas, United States
• Children's Hospital and Regional Medical Center - Seattle — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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