Fludarabine, Carboplatin, and Topotecan in Treating Patients With Relapsed/Refractory Acute Leukemia or Advanced Myelodysplastic Syndrome

Completed · Phase 1

Conditions studied: Leukemia, Myelodysplastic Syndromes

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of fludarabine, carboplatin, and topotecan in treating patients who have relapsed or refractory acute leukemia or advanced myelodysplastic syndrome.

Key facts

Study ID

NCT00005593

Run by

Case Comprehensive Cancer Center

People needed

31

Starts

1998-09-01

Expected to finish

2003-03-01

Last updated by the study team

2010-06-11

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Ireland Cancer Center at University Hospitals Case Medical Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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