Genetic Epidemiology of Responses to Antihypertensives
Completed
Conditions studied: Cardiovascular Diseases, Heart Diseases, Hypertension
In brief
To determine whether measured variation in genes coding for components of vasoconstriction and volume regulating systems predict interindividual differences in blood pressure response to therapy with a thiazide diuretic, hydrochlorothiazide, or an angiotensin II receptor blocker, candesartan, in hypertensive African-Americans (N=300 treated with each drug) and in hypertensive European Americans (N=300 treated with each drug).
Key facts
- Study ID
- NCT00005520
- Run by
- Mayo Clinic
- People needed
- 1200
- Starts
- 1997-02-01
- Expected to finish
- 2008-01-01
- Last updated by the study team
- 2013-01-17
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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