Repetitive Transcranial Magnetic Stimulation for "Voices"

Completed · Phase 2 · Has a placebo group

Conditions studied: Schizophrenia

In brief

OBJECTIVES: I. Determine the effect of repetitive transcranial magnetic stimulation on treatment refractory auditory hallucinations of patients with schizophrenia.

Key facts

Study ID

NCT00004980

Run by

Yale University

People needed

50

Starts

1999-12-01

Expected to finish

2005-06-01

Last updated by the study team

2013-08-07

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of schizophrenia or schizoaffective disorder based on DSM-IV version of SCID
• Auditory hallucinations of spoken speech occurring at least 5 times per day where subject able to discern verbal content
• Right-handed
• At least 4 weeks on stable antipsychotic medication

You may not qualify if…

• history of seizure (unless due to drug withdrawal or medication that is no longer prescribed)
• history of epilepsy in first degree relatives
• estimated IQ less than 80
• unable to provide informed consent
• significant unstable medical condition
• current treatment with clozapine or bupropion
• cochlear implants or other metal in the head (surgical, etc.)
• history of cardiac arrhythmia
• cardiac pacemaker
• active drug or alcohol abuse within prior 6 weeks
• pregnancy

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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