Ketogenic Diet for Child Epilepsy and Seizure Control

Completed · Not applicable

Conditions studied: Epilepsy, Seizures, Lennox-Gastaut Syndrome

In brief

Twenty to thirty percent of children with epilepsy continue to suffer from seizures, even when treated with currently available anticonvulsant medications. Children with Lennox-Gastaut Syndrome (LGS) are particularly handicapped by atonic-myoclonic seizures. Preliminary data suggest that even when other medications have failed, these seizures may respond rapidly and dramatically to a high-fat-low-carbohydrate ketogenic diet. The purpose of the study is to assess if the classic ketogenic diet is efficacious in reducing seizure frequency, medication toxicity, and improves quality of life.

Key facts

Study ID

NCT00004729

Run by

National Institute of Neurological Disorders and Stroke (NINDS)

Starts

1997-07-01

Last updated by the study team

2006-12-22

Who can join

Age: 1 and older, up to 10. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >15 myoclonic or atonic seizures a day
• EEG with Lennox-Gastaut pattern

You may not qualify if…

• <15 atonic or myoclonic seizures a day
• on >3 medications
• previously on diet and/or evidence of metabolic disorder

Where it is running

• Johns Hopkins Hospital — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.