Randomized Study of Sequential Orbital Radiotherapy for Graves' Ophthalmopathy
Completed · Not applicable · Has a placebo group
Conditions studied: Graves' Disease
In brief
OBJECTIVES: I. Evaluate the effects of 20 Gy of external-beam radiotherapy to 1 orbit vs. the untreated orbit at 3 and 6 months after therapy in patients with Graves' ophthalmopathy. II. Evaluate whether 20 Gy of external-beam radiotherapy delivered to the second orbit 6 months later in the course of the disease produces effects of equal magnitude to those observed when the first orbit was treated. III. Relate the magnitude of treatment effects to the time since onset of eye symptoms. IV. Evaluate whether characteristics of radiation retinopathy are present 3 years after orbital radiotherapy.
Key facts
- Study ID
- NCT00004660
- Run by
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- People needed
- 42
- Starts
- 1993-06-01
- Expected to finish
- 1998-01-01
- Last updated by the study team
- 2017-05-30
Who can join
Age: 30 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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